ASYMMETRIC-SYNTHESIS OF TRANSFUSED OCTAHYDRO PYRANO-PYRAN SUBUNITS RELATED TO MARINE POLYETHER TOXINS

被引：6

作者：

DESMAELE, D

PAIN, G

DANGELO, J

机构：

来源：

TETRAHEDRON-ASYMMETRY | 1992年 / 3卷 / 07期

关键词：

STEREOSELECTIVE REDUCTIONS OF 2,2-DIALKYLTETRAHYDROPYRAN-3-ONES; B-CHLORODIISOPINOCAMPHEYLBORANE; STEREOSELECTIVE INTRAMOLECULAR HETERO-MICHAEL ADDITION; MARIN POLYETHER TOXINS;

D O I：

10.1016/S0957-4166(00)82186-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Stereoselective reductions of compound 5, by means of(+)-B-chlorodiisopinocampheylborane led to 6 with a good selectivity. Intramolecular hetero-Michael cyclization of 13 with NaH in HMPA gave 14 with an excellent selectivity.

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页码：867 / 870

页数：4

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