SUBSTITUENT EFFECTS OF BENZOPYRAN-4-(N-CYANO)CARBOXAMIDINE POTASSIUM CHANNEL OPENERS FOR SELECTIVITY TO GUINEA-PIG TRACHEALIS

被引：11

作者：

ISHIZAWA, T ^{[1
]}

KOGA, H ^{[1
]}

SATO, H ^{[1
]}

MAKINO, T ^{[1
]}

TAKA, N ^{[1
]}

TAKAHASHI, T ^{[1
]}

SATO, T ^{[1
]}

NABATA, H ^{[1
]}

机构：

[1] CHUGAI PHARMACEUT CO LTD, FUJI GOTEMBA RES LABS, GOTEMBA, SHIZUOKA 412, JAPAN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 16期

关键词：

D O I：

10.1016/S0960-894X(01)80551-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

6-Substituted benzopyran-4-(N-cyano)amidines 1 and their analogs have been synthesized. Some of these compounds, 1a, 1e, 1f exhibited selective activity for guinea pig trachealis.

引用

页码：1995 / 1998

页数：4

共 13 条

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