DETECTION OF HEPATITIS-E VIRUS-INFECTIONS AMONG DOMESTIC SWINE IN THE KATHMANDU VALLEY OF NEPAL

被引：141

作者：

CLAYSON, ET

INNIS, BL

MYINT, KSA

NARUPITI, S

VAUGHN, DW

GIRI, S

RANABHAT, P

SHRESTHA, MP

机构：

[1] WALTER REED ARMY INST RES, DEPT VIRUS DIS, WASHINGTON, DC 20307 USA

[2] INFECT DIS HOSP, KATMANDU, NEPAL

[3] USA MED COMPONENT, ARMED FORCES RES INST MED SCI, DEPT VIROL, BANGKOK, THAILAND

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 1995年 / 53卷 / 03期

关键词：

D O I：

10.4269/ajtmh.1995.53.228

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The prevalence of hepatitis E virus (HEV) infections among 55 domestic swine living in the Kathmandu Valley of Nepal was investigated. Sera and stool specimens were collected from 47 free-roaming swine and examined for the presence of HEV genomic sequences by the reverse transcription-polymerase chain reaction. Sera from these animals, as well as sera from eight other swine, were also examined for the presence of HEV-specific antibodies by an enzyme-linked immunosorbent assay and by a fluorescent antibody blocking assay. Hepatitis E virus RNA was detected in the sera and/or stool of three of 47 swine, while HEV-specific antibodies were detected in 18 of 55 swine. These results indicate that HEV is a zoonotic virus, and that swine are among its natural hosts.

引用

页码：228 / 232

页数：5

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