EXTRACORPOREAL CARBON-DIOXIDE REMOVAL PERFORMED WITH SURFACE-HEPARINIZED EQUIPMENT IN PATIENTS WITH ARDS

被引：24

作者：

BINDSLEV, L ^{[1
]}

BOHM, C ^{[1
]}

JOLIN, A ^{[1
]}

JONZON, KH ^{[1
]}

OLSSON, P ^{[1
]}

RYNIAK, S ^{[1
]}

机构：

[1] KAROLINSKA HOSP, DEPT EXPTL SURG, S-10401 STOCKHOLM 60, SWEDEN

来源：

ACTA ANAESTHESIOLOGICA SCANDINAVICA | 1991年 / 35卷

关键词：

ADULT RESPIRATORY DISTRESS SYNDROME (ARDS); MULTIPLE ORGAN FAILURE (MOF); EXTRACORPOREAL LUNG ASSISTANCE (ECLA); SURFACE HEPARINIZATION;

D O I：

10.1111/j.1399-6576.1991.tb03409.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

To avoid the drawbacks of systemic anticoagulation during prolonged extracorporeal circulation in patients with adult respiratory distress syndrome (ARDS) a heparinization technique has been developed by which partially degraded heparin can be covalently end-point attached to the surface of the equipment constituting the extracorporeal circuit (Carmeda Bio-Active Surface, CBAS) thereby localizing the anticoagulatory effect. Since 1986 we have used extracorporeal circuits and membrane lungs coated with the CBAS for extracorporeal lung assistance (ECLA) in 14 patients suffering from ARDS. The patients were on ECLA for 3 to 55 days with a survival rate of 43%. Our experience so far is that by using equipment coated with CBAS it is possible to perform long-term extracorporeal circulation with a minimum of intravenously administered heparin, thus avoiding the risk of major coagulation defects.

引用

页码：125 / 131

页数：7

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