Genetic variation and quasi-species

被引：40

作者：

Domingo, Esteban ^{[1
]}

机构：

[1] Univ Autonoma Madrid, Ctr Biol Mol, CSIC, E-28049 Madrid, Spain

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1992年 / 2卷 / 01期

关键词：

FMDV; foot-and-mouth disease virsus; HIV; human immunodeficiency virus; MAR; monoclonal antibody-resistant; vesicular stomatitis virus; VSV;

D O I：

10.1016/S0959-437X(05)80323-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

During the past year the relative fitness, that is, overall replication ability, and the fitness gain of animal virus variants have been quantified, providing new insight into the dynamics for the generation of RNA virus quasi-species. Measurements of mutant frequencies and rates of genetic diversification have confirmed the extreme complexity of RNA virus and retrovirus populations.

引用

页码：61 / 63

页数：3

共 28 条

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