COMPUTER-ASSISTED PERCEPTION OF SIMILARITY USING THE CHIRON PROGRAM - A POWERFUL TOOL FOR THE ANALYSIS AND PREDICTION OF BIOGENETIC PATTERNS

被引：18

作者：

HANESSIAN, S

BOTTA, M

LAROUCHE, B

BOYAROGLU, A

机构：

[1] Department of Chemistry, Université de Montréal, Station A, Montréal, H3C 3J7, Quebec

来源：

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES | 1992年 / 32卷 / 06期

关键词：

D O I：

10.1021/ci00010a020

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The stereochemical and functional patterns in a family of complex natural products derived from a common biosynthetic pathway can be easily visualized through the generation of Fischer and extended projections using the Chiron computer program. Application of this protocol to a series of polyether antibiotics reveals interesting trends in their patterns of substitution as well as in stereochemical relationships.

引用

页码：718 / 722

页数：5

共 42 条

[31] X-RAY CRYSTAL-STRUCTURE OF THALLIUM SALT OF CARRIOMYCIN, A NEW POLYETHER ANTIBIOTIC [J].