NEUROCHEMICAL AND SOME RELATED PSYCHOPHARMACOLOGICAL ASPECTS OF TOURETTES-SYNDROME - AN UPDATE

被引：12

作者：

BAKER, GB ^{[1
]}

CHOKKA, PR ^{[1
]}

BORNSTEIN, RA ^{[1
]}

机构：

[1] OHIO STATE UNIV, DEPT PSYCHIAT, COLUMBUS, OH 43210 USA

来源：

JOURNAL OF PSYCHOPHARMACOLOGY | 1995年 / 9卷 / 03期

关键词：

ACETYLCHOLINE; AMINO ACIDS; ANDROGENIC HORMONES; BETA-PHENYLETHYLAMINE; CATECHOLAMINES; CYCLIC AMP; DYNORPHIN; KYNURENINE; SEROTONIN; TOURETTES SYNDROME; TRYPTAMINE; REVIEW;

D O I：

10.1177/026988119500900311

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Neurochemical investigations of Tourette's syndrome (TS) suggest that the symptoms of this disorder may be the result of an imbalance among several neurotransmitter and/or neuromodulator systems. Neurochemicals which have been studied included: catecholamines; acetylcholine; tryptophan and its metabolites; the amino acids gamma-aminobutyric acid (GABA), glutamate, phenylalanine and p-tyrosine; trace amines; opioid peptides; cyclic AMP and androgenic hormones. A suitable animal model of TS would do much to advance our understanding of this disorder, and there are some interesting recent developments in this regard.

引用

页码：273 / 280

页数：8

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