EFFECT OF HYDROXYL GROUP CONFIGURATION IN HYDROXYETHYLAMINE DIPEPTIDE ISOSTERES ON HIV PROTEASE INHIBITION - EVIDENCE FOR MULTIPLE BINDING MODES

被引：133

作者：

RICH, DH

SUN, CQ

PRASAD, JVNV

PATHIASSERIL, A

TOTH, MV

MARSHALL, GR

CLARE, M

MUELLER, RA

HOUSEMAN, K

机构：

[1] UNIV WISCONSIN,DEPT CHEM,MADISON,WI 53706

[2] WASHINGTON UNIV,SCH MED,DEPT MED,ST LOUIS,MO 63110

[3] GD SEARLE & CO,RES & DEV,DEPT MOLEC & CELL BIOL,SKOKIE,IL 60077

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1991年 / 34卷 / 03期

关键词：

D O I：

10.1021/jm00107a049

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：1222 / 1225

页数：4

共 27 条

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[26] X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A COMPLEX BETWEEN A SYNTHETIC PROTEASE OF HUMAN IMMUNODEFICIENCY VIRUS-1 AND A SUBSTRATE-BASED HYDROXYETHYLAMINE INHIBITOR [J].

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[27]

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