NUCLEOTIDE-SEQUENCE OF THE CHLORAMPHENICOL RESISTANCE DETERMINANT OF THE STREPTOCOCCAL PLASMID PIP501

被引：23

作者：

TRIEUCUOT, P

DECESPEDES, G

HORAUD, T

机构：

[1] Laboratoire des Staphylocoques et des Streptocoques, Institut Pasteur

来源：

PLASMID | 1992年 / 28卷 / 03期

关键词：

D O I：

10.1016/0147-619X(92)90060-N

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We have sequenced the chloramphenicol resistance determinant (cat) of plasmid pIP501 from Streptococcus agalactiae to investigate its relationship with other cognate cat determinants. Sequence analysis revealed that it exhibits a high degree of similarity with the cat genes of plasmids pC221 and pUB112 from Staphylococcus aureus and pSCS1 from Staphylococcus intermedius. These genes, however, display several differences in their regulatory and coding regions. These results demonstrate that the cat determinant of plasmid pIP501 belongs to the pC221 subgroup of CAT variants. © 1992.

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页码：272 / 276

页数：5

相关论文

共 20 条

[1] RELATIONSHIP BETWEEN THE CLOSTRIDIUM-PERFRINGENS CATQ GENE-PRODUCT AND CHLORAMPHENICOL ACETYLTRANSFERASES FROM OTHER BACTERIA [J].

BANNAM, TL ;

ROOD, JI .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1991, 35 (03) :471-476

[2] PLASMID PGB301, A NEW MULTIPLE RESISTANCE STREPTOCOCCAL CLONING VEHICLE AND ITS USE IN CLONING OF A GENTAMICIN-KANAMYCIN RESISTANCE DETERMINANT [J].

BEHNKE, D ;

GILMORE, MS ;

FERRETTI, JJ .

MOLECULAR & GENERAL GENETICS, 1981, 182 (03) :414-421

[3] REGULATION OF THE INDUCIBLE CHLORAMPHENICOL ACETYLTRANSFERASE GENE OF THE STAPHYLOCOCCUS-AUREUS PLASMID PUB112 [J].

BRUCKNER, R ;

MATZURA, H .

EMBO JOURNAL, 1985, 4 (09) :2295-2300

[4] STREPTOCOCCAL-R PLASMID-PIP501 - ENDONUCLEASE SITE MAP, RESISTANCE DETERMINANT LOCATION, AND CONSTRUCTION OF NOVEL DERIVATIVES [J].

EVANS, RP ;

MACRINA, FL .

JOURNAL OF BACTERIOLOGY, 1983, 154 (03) :1347-1355

[5] STRUCTURAL RELATIONSHIPS AMONG CHLORAMPHENICOL-RESISTANCE PLASMIDS OF STAPHYLOCOCCUS-AUREUS [J].

GILLESPIE, MT ;

SKURRAY, RA .

FEMS MICROBIOLOGY LETTERS, 1988, 51 (2-3) :205-210

[6] THE FAMILY OF HIGHLY INTERRELATED SINGLE-STRANDED DEOXYRIBONUCLEIC-ACID PLASMIDS [J].

GRUSS, A ;

EHRLICH, SD .

MICROBIOLOGICAL REVIEWS, 1989, 53 (02) :231-241

[7]

HARDING SE, 1987, BIOCHEM SOC T, V15, P513

[8] MOLECULAR-GENETICS OF RESISTANCE TO MACROLIDES, LINCOSAMIDES AND STREPTOGRAMIN-B (MLS) IN STREPTOCOCCI [J].

HORAUD, T ;

LEBOUGUENEC, C ;

PEPPER, K .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1985, 16 :111-135

[9] R-PLASMIDS IN STREPTOCOCCUS-AGALACTIAE (GROUP-B) [J].

HORODNICEANU, T ;

BOUANCHAUD, DH ;

BIETH, G ;

CHABBERT, YA .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1976, 10 (05) :795-801

[10] GENETIC-ANALYSIS OF THE CONJUGAL TRANSFER DETERMINANTS ENCODED BY THE STREPTOCOCCAL BROAD-HOST-RANGE PLASMID PIP501 [J].

KRAH, ER ;

MACRINA, FL .

JOURNAL OF BACTERIOLOGY, 1989, 171 (11) :6005-6012