SOFT LENS LUBRICANTS AND PRELENS TEAR FILM STABILITY

被引：22

作者：

GOLDING, TR

EFRON, N

BRENNAN, NA

机构：

[1] Corneal Biophysics Laboratory, Department of Optometry, University of Melbourne, Parkville

来源：

OPTOMETRY AND VISION SCIENCE | 1990年 / 67卷 / 06期

关键词：

Dry eye; Hema contact lenses; Prelens tear film; Rewetting solutions; Tear break-up time;

D O I：

10.1097/00006324-199006000-00011

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Soft contact lens wearers complaining of “dry eye” are frequently prescribed rewetting drops, although the mode of action and efficacy of this treatment have not been established. Enhancement of prelens tear film (PLTF) stability could provide a basis for symptomatic relief with solution instillation. Thirty symptomatic hydroxyethyl methacrylate (HEMA) lens wearers participated in 4 separate trials of no solution (baseline), saline, and 2 soft lens lubricants. Solutions were applied for a 6-h adaptation period, and PLTF noninvasive break-up time (NIBUT) was monitored for 1 h after a final instillation. PLTF NIBUT was significantly elevated 1 min after instillation of all solutions (p<0.001, logrank test) but this effect persisted for less than 5 min. The transient enhancement of PLTF stability arising from the instillation of these rewetting solutions is unlikely to provide a basis for prolonged symptomatic relief. © 1990 American Academy of Optometry.

引用

页码：461 / 465

页数：5

共 14 条

[11]

Armltage P., Bery G., Statistical Methods in Medical Research, pp. 421-439, (1987)

[12]

Bourassa S., Benjamin W.J., Clinical findings correlated with contact angles on rigid gas permeable contact lens surfaces in vivo, J am Optom Assoc, 60, pp. 584-590, (1989)

[13]

Guillon J.P., Guillon M., Tear film examination of the contact lens patient, Contax, May, pp. 14-18, (1988)

[14]

Yeager M.D., Benjamin W.J., Care regimens and initial wetting of a silicone/acrylate surface in vivo, Int Contact Lens Clin, 14, pp. 58-61, (1987)

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