SYNTHESIS OF THE SESQUITERPENE (+/-)-CERATOPICANOL - USE OF RADICALS DERIVED FROM EPOXIDES

被引：53

作者：

CLIVE, DLJ

MAGNUSON, SR

机构：

[1] Department of Chemistry, University of Alberta, Edmonton

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 01期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/0040-4039(94)02158-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The sesquiterpene (+/-)-ceratopicanol [(+/-)-1] was synthesized by a route based on Claisen rearrangement (7 --> 8) and radical cyclization (16 alpha, 16 beta --> 17 alpha, 17 beta). Certain limitations on vinyl radical cyclization were observed, and so the required radical was generated by titanium-induced opening of an epoxide.

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页码：15 / 18

页数：4

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