INFECTIOUS BUT NON-LEUKEMOGENIC FRIEND LEUKEMIA VIRUS OBTAINED AFTER PROLONGED CULTIVATION IN VITRO

被引：22

作者：

YOSHIKURA, H

HIROKAWA, Y

IKAWA, Y

SUGANO, H

机构：

[1] Department of Pathology, National Institute of Health, Tokyo, Shinagawa-ku

[2] Department of Pathology, Cancer Institute, Japanese Foundation of Cancer Research, Tokyo, Toshima-ku

[3] Institut du Radium, Faculté des Sciences, Orsay

来源：

INTERNATIONAL JOURNAL OF CANCER | 1969年 / 4卷 / 05期

关键词：

D O I：

10.1002/ijc.2910040508

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A non‐leukemogenic strain of Friend leukemia virus (FLV) propagated in vitro interfered with infection by murine sarcoma virus (Moloney) (MSV) and acted as a helper of defective MSV. This suggests that the non‐leukemogenic strain of FLV is infectious. After prolonged propagation in vitro, the leukemogenicity of a highly leukemogenic strain of FLV gradually decreased, while the infectivity assayed by interference with MSV infection remained unchanged. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company

引用

页码：636 / +

页数：1