CATABOLISM OF TAURINE IN PSEUDOMONAS-AERUGINOSA

被引：43

作者：

SHIMAMOTO, G ^{[1
]}

BERK, RS ^{[1
]}

机构：

[1] WAYNE STATE UNIV,SCH MED,DEPT IMMUNOL & MICROBIOL,DETROIT,MI 48202

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 569卷 / 02期

关键词：

Ethyl methane sulfonate; Sulfoacetaldehyde; Taurine catabolism; Transaminase;

D O I：

10.1016/0005-2744(79)90064-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cell-free extracts of taurine-grown Pseudomonas aeruginosa catalyze the transamination of taurine and pyruvate resulting in the formation of l-alanine and sulfoacetaldehyde. The enzyme responsible for this activity has been partially purified in order to demonstrate its participation in a pathway of taurine degradation. Ethyl methane sulfonate treatment of Ps. aeruginosa yielded a mutant deficient in taurine transaminase and incapable of growing on taurine indicating that the enzyme is of physiological significance in this organism. © 1979.

引用

页码：287 / 292

页数：6