PREGNANCY ASSOCIATED WITH LUPUS ANTICOAGULANT AND HEPARIN INDUCED THROMBOCYTOPENIA - MANAGEMENT WITH A LOW-MOLECULAR-WEIGHT HEPARINOID

被引：26

作者：

VANBESIEN, K ^{[1
]}

HOFFMAN, R ^{[1
]}

GOLICHOWSKI, A ^{[1
]}

机构：

[1] INDIANA UNIV HOSP,DEPT OBSTET & GYNECOL,INDIANAPOLIS,IN 46202

来源：

THROMBOSIS RESEARCH | 1991年 / 62卷 / 1-2期

关键词：

D O I：

10.1016/0049-3848(91)90665-J

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The management of pregnant patients with coagulopathies and heparin induced thrombocytopenia is difficult and poorly defined. We report the case of a patient who was treated with a low molecular weight heparinoid. The treatment was complicated by the delayed occurrence of thrombocytopenia and a thrombotic event. This is the first report of thrombocytopenia caused by heparinoid. It is possible that this complication could have been avoided by a shorter duration of treatment with heparinoid and the use of Vitamin K antagonists during the second trimester of pregnancy.

引用

页码：23 / 29

页数：7

共 38 条

[31]

SHERLOCK S, DISORDERS LIVER BILA, P213

[32] HETEROGENEITY OF HEPARIN LOTS ASSOCIATED WITH THROMBOCYTOPENIA AND THROMBOEMBOLISM [J].

STEAD, RB ;

SCHAFER, AI ;

ROSENBERG, RD ;

HANDIN, RI ;

JOSA, M ;

KHURI, SF .

AMERICAN JOURNAL OF MEDICINE, 1984, 77 (01) :185-188

[33] SAFETY AND PHARMACOKINETICS OF THE LOW-MOLECULAR WEIGHT HEPARINOID ORG-10172 ADMINISTERED TO HEALTHY ELDERLY VOLUNTEERS [J].

STIEKEMA, JCJ ;

WIJNAND, HP ;

VANDINTHER, TG ;

MOELKER, HCT ;

DAWES, J ;

VINCHENZO, A ;

TOEBERICH, H .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1989, 27 (01) :39-48

[34]

TENCATE H, 1984, CLIN CHEM, V30, P860

[35] LABORATORY IDENTIFICATION OF THE LUPUS ANTICOAGULANT [J].

TRIPLETT, DA ;

BRANDT, J .

BRITISH JOURNAL OF HAEMATOLOGY, 1989, 73 (02) :139-142

[36] LUPUS ANTICOAGULANT AND THROMBOSIS OF THE HEPATIC VEINS - (BUDD-CHIARI SYNDROME) - REPORT OF 3 PATIENTS AND REVIEW OF THE LITERATURE [J].

VANSTEENBERGEN, W ;

BEYLS, J ;

VERMYLEN, J ;

FEVERY, J ;

MARCHAL, G ;

DESMET, V ;

DEGROOTE, J .

JOURNAL OF HEPATOLOGY, 1986, 3 (01) :87-94

[37]

VITOUX JF, 1986, THROMB HAEMOSTASIS, V55, P37

[38] HEPARIN AND PLATELETS [J].

WARKENTIN, TE ;

KELTON, JG .

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 1990, 4 (01) :243-264

← 1 2 3 4 →