PH-POSITIVE CHRONIC MYELOID-LEUKEMIA WITH T(8-21)(Q22-Q22) IN BLASTIC CRISIS

被引：29

作者：

FERRO, MT

STEEGMAN, JL

ESCRIBANO, L

HEIURICHS, B

PARADA, L

GARCIASAGREDO, JM

RESINO, M

CABELLO, P

SANROMAN, C

机构：

[1] HOSP RAMON Y CAJAL,DEPT HEMATOL,MADRID,SPAIN

[2] HOSP PRINCESA,DEPT HEMATOL,MADRID,SPAIN

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 58卷 / 01期

关键词：

D O I：

10.1016/0165-4608(92)90143-V

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A patient diagnosed with chronic myeloid leukemia was studied periodically during his illness. The result showed the presence of a Philadelphia (Ph) chromosome by a 9;22 translocation as a single abnormality to the time of blastic crisis. At that time, the chromosome studies showed a clonal evolution. Furthermore, a second derivated line was added to the Ph line. This new anomaly consisted of a 8;21 translocation, considered as specific of M2 type acute nonlymphoblastic leukemia of French-American-British classification.

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页码：96 / 99

页数：4

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