IDENTIFICATION OF AMINOPHOSPHOLIPID STEREOMERS BY POSITIVE-ION FAST-ATOM-BOMBARDMENT COMBINED WITH COLLISIONAL ACTIVATION MASS-ANALYZED ION KINETIC-ENERGY ANALYSIS AND HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：4

作者：

CHEN, S ^{[1
]}

MENON, G ^{[1
]}

TRALDI, P ^{[1
]}

机构：

[1] CNR,MASS SPECTROMETRY SERV,I-35120 PADUA,ITALY

来源：

ORGANIC MASS SPECTROMETRY | 1992年 / 27卷 / 03期

关键词：

D O I：

10.1002/oms.1210270311

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two methods for the identification of aminophospholipid stereomers are described. After a chemical derivatization, 9-fluorenylmethoxycarbonyl derivatives of diacyl-sn-2- and diacyl-sn-3-phosphoserine and diacyl-sn-2- and diacyl-sn-3-phosphoethanolamine can be characterized by positive-ion fast atom bombardment combined with collisional activation mass-analysed ion kinetic energy analysis based on the differentiation of relative abundances [M + H + diethanolamine - 89]+ and [M + H]+ fragments derived from (M + H + diethanolamine]+ ions, the protonated solvated molecules, and normal phase high-performance liquid chromatography on the basis of different elution times of the derivatives of the aminophospholipid stereomers on an aminopropyl-bonded column.

引用

页码：215 / 218

页数：4

共 14 条

[1] CHEMICAL SYNTHESIS OF SOME LECITHIN ANALOGS POTENTIAL INHIBITORS OF PHOSPHOLIPASE A [J].