GUANOSINE TETRAPHOSPHATE - COORDINATOR OF METABOLIC RESPONSE TO NITROGEN STARVATION IN ENTEROBACTERIA

被引：25

作者：

BRIDGER, WA

PARANCHYCH, W

机构：

[1] William A. Bridger and William Paranchych are, the Department of Biochemistry, University of Edmonton, Edmonton

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1979年 / 4卷 / 08期

关键词：

D O I：

10.1016/0968-0004(79)90418-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Deprivation of amino acids brings about major adjustments in bacterial metabolism that are designed to counteract the emergency. These are mediated by pleiotropic regulatory effects of guanosine tetraphosphate (ppGpp), and are felt at the levels of ribosome and membrane biosynthesis, intermediary metabolism and protein turnover. Regulation by ppGpp involves both control of gene expression and allosteric effects on enzyme activity. © 1979.

引用

页码：176 / 179

页数：4

共 27 条

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