AN INSIGHT INTO THE ACTIVE-SITE OF PSEUDOMONAS-FLUORESCENS (P-CEPACIA) LIPASE TO DEFINE THE STEREOCHEMICAL DEMAND FOR THE TRANSESTERIFICATION IN ORGANIC-SOLVENTS

被引：22

作者：

FERRABOSCHI, P

CASATI, S

DEGRANDI, S

GRISENTI, P

SANTANIELLO, E

机构：

[1] Dipartimento di Chimica e Biochimica Medica Via Saldini, 50-20133, Milano

来源：

BIOCATALYSIS | 1994年 / 10卷 / 1-4期

关键词：

PSEUDOMONAS FLUORESCENS LIPASE; PSEUDOMONAS CEPACIA LIPASE; ENZYMATIC TRANSESTERIFICATION; ENANTIOSELECTIVITY;

D O I：

10.3109/10242429409065237

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Pseudomonas fluorescens lipase-catalyzed transesterification of 2-methyl alkanols 1 and the 2-substituted oxiranemethanols 2 with vinyl acetate in organic solvents has been studied and the results discussed in terms of steric and electronic demand within the recently postulated models of the lipase active site.

引用

收藏

页码：279 / 288

页数：10

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