HB AL-AIN ABU-DHABI [ALPHA-18(A16)GLY-]ASP] - A NEW HEMOGLOBIN-VARIANT DISCOVERED IN AN EMIRATEE FAMILY

被引：9

作者：

ABBES, S

MRAD, A

FITZGERALD, PA

DORMER, P

BLOUQUIT, Y

KISTER, J

GALACTEROS, F

WAJCMAN, H

机构：

[1] HOP BICETRE,INSERM,U299,F-94275 LE KREMLIN BICETR,FRANCE

[2] AL TAWAM HOSP,DEPT HEMATOL,AL AIN,U ARAB EMIRATES

[3] HOP HENRI MONDOR,INSERM,U91,F-94010 CRETEIL,FRANCE

[4] AL TAWAM HOSP,DEPT INTERNAL MED,AL AIN,U ARAB EMIRATES

来源：

HEMOGLOBIN | 1992年 / 16卷 / 05期

关键词：

D O I：

10.3109/03630269209005687

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

During a routine program of hemoglobin screening performed in the United Arab Emirates, we observed an electrophoretically fast-moving variant in a 9-month-old girl and in several members of her family. The structural determination, performed by reversed phase high performance liquid chromatography and amino acid sequencing, revealed a new variant that we named Hb Al-Ain Abu Dhabi [alpha-18(A16) Gly-->Asp]. Its functional properties were normal.

引用

页码：355 / 362

页数：8

共 14 条

[11] RADOLA BJ, 1973, ANN NY ACAD SCI, V209, P127, DOI 10.1111/j.1749-6632.1973.tb47523.x
[12] SCHNEIDER RG, 1986, CRC HDB SERIES, V4, P125
[13] CLEAVAGE BY PROTEASE FROM STAPHYLOCOCCUS-AUREUS V8 - AN IMPROVEMENT IN THE SEQUENCE-ANALYSIS OF HUMAN HEMOGLOBIN-VARIANTS
VASSEUR, C
GALACTEROS, F
GROFF, P
WAJCMAN, H
[J]. JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS, 1991, 22 (03): : 195 - 205
[14] RED-CELL GENETIC ABNORMALITIES IN PENINSULAR ARABS - SICKLE HEMOGLOBIN, G6PD DEFICIENCY, AND ALPHA-THALASSEMIA AND BETA-THALASSEMIA
WHITE, JM
BYRNE, M
RICHARDS, R
BUCHANAN, T
KATSOULIS, E
WEERASINGH, K
[J]. JOURNAL OF MEDICAL GENETICS, 1986, 23 (03) : 245 - 251

← 1 2 →