CUMULATIVE EFFECT OF SURFACTANTS ON CUTANEOUS HORNY LAYERS - ADSORPTION ONTO HUMAN KERATIN LAYERS INVIVO

被引：31

作者：

IMOKAWA, G

MISHIMA, Y

机构：

[1] Department of Dermatology, Kobe University School of Medicine, Kobe

来源：

CONTACT DERMATITIS | 1979年 / 5卷 / 06期

关键词：

Adsorption; skin roughness; surfactant;

D O I：

10.1111/j.1600-0536.1979.tb04905.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

An attempt ha been made to determine the adsorption ability of surfactants by the human horny layers in vivo. For this purpose, a technique utilizing an acidic dye such as indigo carmine was applicable and convenient. Our in vivo study estimating adsorbing residual amounts of surfactants has revealed that there is a positive correlation between adsorbing and roughening effects. It is suggested that the pathogenesis of hand roughness is primarily related to the cumulative injury of the stratum corenum by adsorbing residual surfactant molecules. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：357 / 366

页数：10

共 13 条

[1]

GUN A, 1969, ACTA DERMATOVENE S61, V49, P1

[2] DENATURATION OF EPIDERMAL KERATIN BY SURFACE ACTIVE AGENTS [J].