MEROZOITE SURFACE ANTIGEN-I OF PLASMODIUM

被引：88

作者：

COOPER, JA

机构：

[1] Zentrum für Molekulare Biologie, Universität Heidelberg, 6900 Heidelberg

来源：

PARASITOLOGY TODAY | 1993年 / 9卷 / 02期

关键词：

D O I：

10.1016/0169-4758(93)90031-A

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The merozoite is the invasive form of the asexual stage of Plasmodium species. At least two polymorphic glycoproteins have been found on its surface in the human malaria parasite Plasmodium falciparum. The best-characterized of these is known as merozoite surface antigen-1 (MSA1) (185-200 kDa) (Ref. 1). Similar molecules are found in other malaria species. The other merozoite surface antigen, MSA2 (35-48 kDa) (Ref. 2), is distinct from MSA1 but is equally polymorphic. In this review, Juan Cooper condenses the body of structural information on MSA1 known to date. A database compiled from MSA1 sequences from several species used together with sequence comparisons and predicted secondary structure reveals interesting features of this molecule.

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页码：50 / 54

页数：5

相关论文

共 42 条

[11] MAPPING OF THE REGION PREDOMINANTLY RECOGNIZED BY ANTIBODIES TO THE PLASMODIUM-FALCIPARUM MEROZOITE SURFACE-ANTIGEN MSA-1 [J].

COOPER, JA ;

COOPER, LT ;

SAUL, AJ .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1992, 51 (02) :301-312

[12]

COOPER JA, IN PRESS MOL BIOCH P

[13] COMPARISON OF THE CARBOXY-TERMINAL, CYSTEINE-RICH DOMAIN OF THE MEROZOITE SURFACE PROTEIN-1 FROM SEVERAL STRAINS OF PLASMODIUM-YOELII [J].

DALY, TM ;

BURNS, JM ;

LONG, CA .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1992, 52 (02) :279-282

[14] PROCESSING OF A MAJOR PARASITE SURFACE GLYCOPROTEIN DURING THE ULTIMATE STAGES OF DIFFERENTIATION IN PLASMODIUM-KNOWLESI [J].

DAVID, PH ;

HADLEY, TJ ;

AIKAWA, M ;

MILLER, LH .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1984, 11 (APR) :267-282

[15] MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF THE GENE ENCODING THE MAJOR MEROZOITE SURFACE-ANTIGEN OF PLASMODIUM-CHABAUDI-CHABAUDI IP-PC1 [J].

DELEERSNIJDER, W ;

HENDRIX, D ;

BENDAHMAN, N ;

HANEGREEFS, J ;

BRIJS, L ;

HAMERSCASTERMAN, C ;

HAMERS, R .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1990, 43 (02) :231-244

[16] PRIMARY STRUCTURE OF THE MEROZOITE SURFACE ANTIGEN-1 OF PLASMODIUM-VIVAX REVEALS SEQUENCES CONSERVED BETWEEN DIFFERENT PLASMODIUM SPECIES [J].

DELPORTILLO, HA ;

LONGACRE, S ;

KHOURI, E ;

DAVID, PH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (09) :4030-4034

[17]

FERGUSON MAJ, 1988, ANNU REV BIOCHEM, V57, P285

[18] STRUCTURE AND EXPRESSION OF THE GENE FOR PV200, A MAJOR BLOOD-STAGE SURFACE-ANTIGEN OF PLASMODIUM-VIVAX [J].

GIBSON, HL ;

TUCKER, JE ;

KASLOW, DC ;

KRETTLI, AU ;

COLLINS, WE ;

KIEFER, MC ;

BATHURST, IC ;

BARR, PJ .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1992, 50 (02) :325-334

[19] THE N-TERMINAL AMINO-ACID SEQUENCES OF THE PLASMODIUM-FALCIPARUM (FCB1) MEROZOITE SURFACE-ANTIGENS OF 42-KILODALTON AND 36-KILODALTON, BOTH DERIVED FROM THE 185-195-KILODALTON PRECURSOR [J].

HEIDRICH, HG ;

MIETTINENBAUMANN, A ;

ECKERSKORN, C ;

LOTTSPEICH, F .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1989, 34 (02) :147-153

[20] PRIMARY STRUCTURE OF THE PRECURSOR TO THE 3 MAJOR SURFACE-ANTIGENS OF PLASMODIUM-FALCIPARUM MEROZOITES [J].

HOLDER, AA ;

LOCKYER, MJ ;

ODINK, KG ;

SANDHU, JS ;

RIVEROSMORENO, V ;

NICHOLLS, SC ;

HILLMAN, Y ;

DAVEY, LS ;

TIZARD, MLV ;

SCHWARZ, RT ;

FREEMAN, RR .

NATURE, 1985, 317 (6034) :270-273

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