SPLIT DECOMPOSITION - A TECHNIQUE TO ANALYZE VIRAL EVOLUTION

被引：50

作者：

DOPAZO, J

DRESS, A

VONHAESELER, A

机构：

[1] UNIV VALENCIA, DEPT GENET, E-46100 BURJASSOT, SPAIN

[2] UNIV BIELEFELD, DEPT MATH, W-4800 BIELEFELD, GERMANY

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1993年 / 90卷 / 21期

关键词：

EVOLUTIONARY TREES; QUASI-SPECIES; OVERLAPPING CLUSTERING;

D O I：

10.1073/pnas.90.21.10320

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A clustering technique allowing a restricted amount of overlapping and based on an abstract theory of coherent decompositions of finite metrics is used to analyze the evolution of foot-and-mouth disease viruses. The emerging picture is compatible with the existence of viral populations with a quasispecies structure and illustrates various forms of evolution of this virus family. In addition, it allows the correlation of these forms with geographic occurrence.

引用

页码：10320 / 10324

页数：5

共 34 条

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MARTINEZ MA, 1992, J VIROL, V66, P3557

[22] IMPLICATIONS OF A QUASISPECIES GENOME STRUCTURE - EFFECT OF FREQUENT, NATURALLY-OCCURRING AMINO-ACID SUBSTITUTIONS ON THE ANTIGENICITY OF FOOT-AND-MOUTH-DISEASE VIRUS [J].