OXIDATIVE POLYCYCLIZATION VERSUS THE POLYEPOXIDE CASCADE - NEW PATHWAYS IN POLYETHER (BIO)SYNTHESIS

被引：23

作者：

KOERT, U

机构：

[1] Fachbereich Chemie, Universität Marburg, D-35032, Hans‐Meerwein‐Strasse

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1995年 / 34卷 / 03期

关键词：

BIOSYNTHESIS; CYCLIZATIONS; OXIDATIONS; POLYETHERS;

D O I：

10.1002/anie.199502981

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

By which route is monensin A biosynthesized? Is an (E.E.E.) triene first epoxidized and the polyepoxide then transformed into the natural product in a cascade of ring openings and ring closures? Or does a (Z.Z.Z.) triene undergo successive oxidative cyclizations to give monensin A directly? New results from McDonald and Towne, who carried out oxidations of (Z) dienes with pyridinium chlorochromate, support the second route. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：298 / 300

页数：3

共 14 条

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