ANTIOXIDANT FUNCTION OF MELANIN IN BLACK FUNGI

被引：79

作者：

JACOBSON, ES

HOVE, E

EMERY, HS

机构：

[1] VIRGINIA COMMONWEALTH UNIV, DEPT INTERNAL MED, RICHMOND, VA 23249 USA

[2] UNIV RICHMOND, DEPT BIOL, RICHMOND, VA 23173 USA

来源：

INFECTION AND IMMUNITY | 1995年 / 63卷 / 12期

关键词：

D O I：

10.1128/IAI.63.12.4944-4945.1995

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

1,8-Dihydroxynaphthalene melanin in Wangiella dermatitidis and Alternaria alternata was titrated in vivo with the oxidants permanganate, hypochlorite, and H2O2. Melanized strains neutralized more oxidant and withstood higher concentrations of permanganate and hypochlorite than albino strains did, H2O2 killing required 1,000-fold higher concentrations, and melanin did not protect W. dermatitidis against H2O2.

引用

页码：4944 / 4945

页数：2

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