ATRAZINE MEASUREMENTS USING SURFACE TRANSVERSE-WAVE DEVICES

被引:49
作者
TOMMOY, M
BAER, RL
SPIRASOLOMON, D
DOHERTY, TP
机构
[1] Chemical Systems Department, Hewlett-Packard Laboratories, Hewlett-Packard Company, Palo Alto, P.O. Box 10350
关键词
D O I
10.1021/ac00105a005
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We have developed a new kind of chemical sensor based on the surface transverse wave device, The sensor resembles a surface acoustic wave sensor with the addition of a metal grating between the transducers and a different crystal orientation. Unlike surface acoustic wave and flexural plate wave devices, no fluid compression is associated with the wave motion, This sensor operates at 250 MHz and is ideally suited to measurements of surface-attached mass under fluid immersion, By immobilizing atrazine to the surface of the sensor device, we demonstrated the detection of atrazine in the range of 0.06 ppb to 10 ppm, The sensor surface was refreshed by dissociating the antibody, and 100 repeated measurements were made. The measurement can be made rapidly (<3 min), in near real time and without the use of labeled reagents.
引用
收藏
页码:1510 / 1516
页数:7
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