Two experiments are reported in which lexical decision time (LDT) was measured for target words related to alcohol. In one experimental condition (A-A) targets were preceded by alcohol related Prime words. In a second condition (0-A) targets were preceded by primes unrelated to alcohol. Experiment 1 found a semantic priming effect (LDT faster in the (A-A) than the (O-A) condition) for participants with a DSM III diagnosis of alcohol dependency but not for an age, sex and vocabulary matched control group of non-dependent drinkers. Experiment 2 compared a heavy drinking but non-dependent group with a light alcohol consumption group. No semantic priming effect was found in either group. It is concluded that the semantic priming paradigm may have value as a clinical tool for the detection of alcohol dependence and the assessment of decline in dependence.