THE USE OF PROSTATE-SPECIFIC ANTIGEN AND PROSTATE-SPECIFIC ANTIGEN DENSITY IN THE DIAGNOSIS OF PROSTATE-CANCER IN A COMMUNITY-BASED UROLOGY PRACTICE

被引：76

作者：

ROMMEL, FM

AGUSTA, VE

BRESLIN, JA

HUFFNAGLE, HW

POHL, CE

SIEBER, PR

STAHL, CA

机构：

[1] Urological Associates of Lancaster, Lancaster, PA

来源：

JOURNAL OF UROLOGY | 1994年 / 151卷 / 01期

关键词：

ANTIGENS; NEOPLASM; PROSTATIC NEOPLASMS;

D O I：

10.1016/S0022-5347(17)34878-4

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Since 1989 we have used serum prostate specific antigen (PSA) levels as an indication for ultrasound guided systematic biopsies of the prostate. Realizing that the PSA level in part reflects prostatic glandular epithelial volume, we reviewed the accumulated data on our last 2,340 biopsies to determine if the quotient of PSA and prostatic volume, prostate specific antigen density, provided any further diagnostic information. There were evaluable data for 2,020 patients. Prostate specific antigen density levels are shown to have a strong correlation with the diagnosis of prostate cancer and provide a more reliable indication for ultrasound guided biopsy of the prostate than PSA alone.

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页码：88 / 93

页数：6

相关论文

共 15 条

[1] THE DISTRIBUTION OF PROSTATE SPECIFIC ANTIGEN IN MEN WITHOUT CLINICAL OR PATHOLOGICAL EVIDENCE OF PROSTATE-CANCER - RELATIONSHIP TO GLAND VOLUME AND AGE [J].

BABAIAN, RJ ;

MIYASHITA, H ;

EVANS, RB ;

RAMIREZ, EI .

JOURNAL OF UROLOGY, 1992, 147 (03) :837-840

[2] THE USE OF PROSTATE SPECIFIC ANTIGEN DENSITY TO ENHANCE THE PREDICTIVE VALUE OF INTERMEDIATE LEVELS OF SERUM PROSTATE SPECIFIC ANTIGEN [J].

BENSON, MC ;

WHANG, IS ;

OLSSON, CA ;

MCMAHON, DJ ;

COONER, WH .

JOURNAL OF UROLOGY, 1992, 147 (03) :817-821

[3] SCREENING FOR PROSTATIC-CARCINOMA WITH PROSTATE SPECIFIC ANTIGEN [J].

BRAWER, MK ;

CHETNER, MP ;

BEATIE, J ;

BUCHNER, DM ;

VESSELLA, RL ;

LANGE, PH .

JOURNAL OF UROLOGY, 1992, 147 (03) :841-845

[4] MEASUREMENT OF PROSTATE-SPECIFIC ANTIGEN IN SERUM AS A SCREENING-TEST FOR PROSTATE-CANCER [J].

CATALONA, WJ ;

SMITH, DS ;

RATLIFF, TL ;

DODDS, KM ;

COPLEN, DE ;

YUAN, JJJ ;

PETROS, JA ;

ANDRIOLE, GL .

NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (17) :1156-1161

[5]

CHAN DW, 1987, CLIN CHEM, V33, P1916

[6] CLINICAL-APPLICATION OF TRANS-RECTAL ULTRASONOGRAPHY AND PROSTATE SPECIFIC ANTIGEN IN THE SEARCH FOR PROSTATE-CANCER [J].

COONER, WH ;

MOSLEY, BR ;

RUTHERFORD, CL ;

BEARD, JH ;

POND, HS ;

BASS, RB ;

TERRY, WJ .

JOURNAL OF UROLOGY, 1988, 139 (04) :758-761

[7] PROSTATE-CANCER DETECTION IN A CLINICAL UROLOGICAL PRACTICE BY ULTRASONOGRAPHY, DIGITAL RECTAL EXAMINATION AND PROSTATE SPECIFIC ANTIGEN [J].

COONER, WH ;

MOSLEY, BR ;

RUTHERFORD, CL ;

BEARD, JH ;

POND, HS ;

TERRY, WJ ;

IGEL, TC ;

KIDD, DD .

JOURNAL OF UROLOGY, 1990, 143 (06) :1146-1154

[8] RANDOM SYSTEMATIC VERSUS DIRECTED ULTRASOUND GUIDED TRANS-RECTAL CORE BIOPSIES OF THE PROSTATE [J].

HODGE, KK ;

MCNEAL, JE ;

TERRIS, MK ;

STAMEY, TA .

JOURNAL OF UROLOGY, 1989, 142 (01) :71-75

[9] SERUM PROSTATE SPECIFIC ANTIGEN AS PRE-SCREENING TEST FOR PROSTATE-CANCER [J].

LABRIE, F ;

DUPONT, A ;

SUBURU, R ;

CUSAN, L ;

TREMBLAY, M ;

GOMEZ, JL ;

EMOND, J ;

STAMEY, TA ;

LANGE, PH .

JOURNAL OF UROLOGY, 1992, 147 (03) :846-852

[10] DETERMINATION OF PROSTATE VOLUME WITH TRANSRECTAL US FOR CANCER SCREENING .1. COMPARISON WITH PROSTATE-SPECIFIC ANTIGEN ASSAYS [J].

LITTRUP, PJ ;

KANE, RA ;

WILLIAMS, CR ;

EGGLIN, TK ;

LEE, F ;

TORPPEDERSEN, S ;

CHURCH, PA .

RADIOLOGY, 1991, 178 (02) :537-542