ENANTIOMER SEPARATION OF ALPHA-CAMPHOLENE AND FENCHOLENE DERIVATIVES BY CAPILLARY GAS-CHROMATOGRAPHY ON PERMETHYLATED CYCLODEXTRIN PHASES .1. COMPOUNDS SEPARABLE WITH SINGLE COLUMNS

alpha-Campholene and fencholene derivatives are compounds with interesting odour properties, e.g. sandalwood and woody notes. They have one (derived from the initial product, alpha-pinene) or several stereogenic centres. The stereoisomers of these compounds may have different odour properties; therefore, analysis methods are developed for the complete separation of the diastereomers and enantiomers. It is shown that the alcohols with one stereogenic centre as well as of the esters and ethers of alpha-campholene and fencholene derivatives with two stereogenic centres can be separated on permethylated alpha- und beta-cyclodextrins dissolved in polysiloxanes. Factors influencing the separation are discussed.