BIOSYNTHESIS OF 6BETA-HYDROXYPROGESTERONE AND 6ALPHA-HYDROXYPROGESTERONE IN HUMAN FOETAL LIVER

被引：25

作者：

LISBOA, BP

GUSTAFSSON, JA

机构：

[1] Karolinska Sjukhwt, Hormonlaboratoriet, Stockholm

[2] Kemiska Institutionen, Karolinska Institutet, Stockholm, S-104 01

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1969年 / 9卷 / 04期

关键词：

D O I：

10.1111/j.1432-1033.1969.tb00637.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

After incubation of progesterone with 105000 Xg microsomes of human foetal liver two C21O3 steroids were isolated by ascending one‐dimensional thin‐layer chromatography. Gas chromato‐graphy‐mass spectrometry analysis showed that the compounds were identical with 6β‐ and 6α‐hydroxyprogesterone. The significance of this finding in relation to earlier reports of 6‐hy‐droxylated C21 steroids in human pregnancy urine is discussed. Copyright © 1969, Wiley Blackwell. All rights reserved

引用

页码：503 / +

页数：1

共 33 条

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