ANALYSIS OF THE NUCLEOTIDE-SEQUENCE OF 53-KBP FROM THE RIGHT TERMINUS OF THE GENOME OF VARIOLA-MAJOR VIRUS-STRAIN INDIA-1967

被引：37

作者：

SHCHELKUNOV, SN

BLINOV, VM

RESENCHUK, SM

TOTMENIN, AV

OLENINA, LV

CHIRIKOVA, GB

SANDAKHCHIEV, LS

机构：

[1] Institute of Molecular Biology, Russian State Research Center NPO Vector, Koltsovo

来源：

VIRUS RESEARCH | 1994年 / 34卷 / 03期

关键词：

ORTHOPOXVIRUS; VARIOLA VIRUS; SEQUENCE ANALYSIS;

D O I：

10.1016/0168-1702(94)90125-2

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Sequencing and computer analysis of a variola major virus strain India-1967 (VAR-IND) genome segment (53,018 bp) from the right terminal region has been carried out. Fifty-nine potential open reading frames (ORFs) of over 60 amino acid residues were identified. Structure-function organization of the VAR-IND DNA segment was compared with the previously reported sequences from the analogous genomic regions of vaccinia virus strains Copenhagen (VAC-COP) and Western Reserve (VAC-WR) and variola virus strain Harvey (VAR-HAR). Multiple differences between VAR-IND and the strains of VAC but the high identity of VAR-IND with VAR-HAR in the genetic maps are revealed. Possible functions of the predicted viral proteins and the effect of their differences on the features of orthopoxviruses are discussed.

引用

收藏

页码：207 / 236

页数：30

相关论文

共 153 条

[41] THE MOUSE NEURONAL CELL-SURFACE PROTEIN-F3 - A PHOSPHATIDYLINOSITOL-ANCHORED MEMBER OF THE IMMUNOGLOBULIN SUPERFAMILY RELATED TO CHICKEN CONTACTIN [J].

GENNARINI, G ;

CIBELLI, G ;

ROUGON, G ;

MATTEI, MG ;

GORIDIS, C .

JOURNAL OF CELL BIOLOGY, 1989, 109 (02) :775-788

[42] INTERLEUKIN-1 RECEPTOR BLOCKADE ATTENUATES THE HOST INFLAMMATORY RESPONSE [J].

GERSHENWALD, JE ;

FONG, Y ;

FAHEY, TJ ;

CALVANO, SE ;

CHIZZONITE, R ;

KILIAN, PL ;

LOWRY, SF ;

MOLDAWER, LL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (13) :4966-4970

[43] LOCALIZATION AND SEQUENCE OF A VACCINIA VIRUS GENE REQUIRED FOR MULTIPLICATION IN HUMAN-CELLS [J].

GILLARD, S ;

SPEHNER, D ;

DRILLIEN, R ;

KIRN, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (15) :5573-5577

[44] THE COMPLETE DNA-SEQUENCE OF VACCINIA VIRUS [J].

GOEBEL, SJ ;

JOHNSON, GP ;

PERKUS, ME ;

DAVIS, SW ;

WINSLOW, JP ;

PAOLETTI, E .

VIROLOGY, 1990, 179 (01) :247-266

[45] COMPLEMENTARY-DNA CLONING OF A RECEPTOR FOR TUMOR-NECROSIS-FACTOR AND DEMONSTRATION OF A SHED FORM OF THE RECEPTOR [J].

HELLER, RA ;

SONG, K ;

ONASCH, MA ;

FISCHER, WH ;

CHANG, D ;

RINGOLD, GM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (16) :6151-6155

[46] MOLECULAR-CLONING OF A CDNA CODING BILIARY GLYCOPROTEIN-I - PRIMARY STRUCTURE OF A GLYCOPROTEIN IMMUNOLOGICALLY CROSSREACTIVE WITH CARCINOEMBRYONIC ANTIGEN [J].

HINODA, Y ;

NEUMAIER, M ;

HEFTA, SA ;

DRZENIEK, Z ;

WAGENER, C ;

SHIVELY, L ;

HEFTA, LJF ;

SHIVELY, JE ;

PAXTON, RJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (18) :6959-6963

[47] LOCALIZATION AND FINE-STRUCTURE OF A VACCINIA VIRUS GENE ENCODING AN ENVELOPE ANTIGEN [J].

HIRT, P ;

HILLER, G ;

WITTEK, R .

JOURNAL OF VIROLOGY, 1986, 58 (03) :757-764

[48] VACCINIA VIRUS HOMOLOGS OF THE SHOPE FIBROMA VIRUS INVERTED TERMINAL REPEAT PROTEINS AND A DISCONTINUOUS ORF RELATED TO THE TUMOR-NECROSIS-FACTOR RECEPTOR FAMILY [J].

HOWARD, ST ;

CHAN, YS ;

SMITH, GL .

VIROLOGY, 1991, 180 (02) :633-647

[49] 2 EARLY VACCINIA VIRUS GENES ENCODE POLYPEPTIDES RELATED TO PROTEIN-KINASES [J].

HOWARD, ST ;

SMITH, GL .

JOURNAL OF GENERAL VIROLOGY, 1989, 70 :3187-3201

[50]

HUGHES SJ, 1991, J BIOL CHEM, V266, P20103

← 1 2 3 4 5 6 7 8 9 10 →