Synthesis of dihydro-2-(2-phenyl-indole-3-yl)-4-aryl-1,5-benzothiazepines

被引：11

作者：

Dandia, A

Sehgal, V

Upreti, M

机构：

[1] Department of Chemistry, University of Rajasthan

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 1995年 / 105卷 / 1-4期

关键词：

benzpthiazepines; antibacterial activity; biological activity; IR; NMR; mass spectra;

D O I：

10.1080/10426509508042051

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of novel dihydro-2-(2-phenyl-indole-3-yl)-4-aryl-1,5-benzothiazepines (III) have been syn the sized by the reaction of 2-aminothiophenol with 2-phenyl-3-(3-aryl-3-oxo-propen-1-yl)-indoles (I) in ethanol and gl. acetic acid mixture. Chalcones (I) were prepared by the reaction of 2-phenyl-1H-indole-3-carboxaldehyde with substituted acetophenones in ethanolic sodium hydroxide. The compounds have been characterized on the basis of elemental and spectral studies and were screened for their antifungal and antibacterial activities.

引用

页码：93 / 99

页数：7