REVISION, BY PROTON, C-13, AND N-15 NMR-SPECTROSCOPY, OF THE STRUCTURE ASSIGNED A BIS(HEXOPYRANOSYL)-AMINE DERIVATIVE

被引:11
作者
COXON, B [1 ]
HOUGH, L [1 ]
机构
[1] UNIV LONDON QUEEN ELIZABETH COLL,DEPT CHEM,LONDON W8 7AH,ENGLAND
关键词
D O I
10.1016/S0008-6215(00)85473-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Structural analysis of the acetylated, minor product of the reaction of methyl 2,3-anhydro-4,6-O-benzylidene-α-d-mannopyranoside with ammonia by high-field proton- and 13C-n.m.r. spectroscopy, and also 15N-n.m.r. spectroscopy, has shown that this acetyl derivative is bis(methyl 2-O-acetyl-4,6-O-benzylidene-3-deoxy-α-d-altropyranosid-3-yl)amine , and not the N-acetyl derivative reported previously. The configuration and conformation of the bis(altropyranosid-3-yl)amine derivative have been determined, and its unusually large 1J15NH coupling constant is discussed. © 1979.
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页码:47 / 57
页数:11
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