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NEW DEVELOPMENTS IN MONOCLONAL-ANTIBODIES FOR CANCER-DETECTION AND THERAPY

被引：32
作者：
GOLDENBERG, DM
机构：
[1] Center for Molecularmedicine and Immunology, Garden state cancer center in Newark, New Jersey
来源：
CA-A CANCER JOURNAL FOR CLINICIANS | 1994年 / 44卷 / 01期
关键词：
D O I：
10.3322/canjclin.44.1.43
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Monoclonal antibodies have provided clinicians with an intriguing, target-specific approach to cancer management. Used alone or conjugated with drugs, toxins, or radionuclides, monoclonal antibodies have been shown to be useful in the detection and/or treatment of several cancers. Recent advances, such as the development of ''humanized'' antibodies, promise to increase their effectiveness even more. This article summarizes the status of the in vivo use of monoclonal antibodies for cancer detection and therapy.
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页码：43 / 64
页数：22
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