共 41 条
[41]
WINN DM, 1984, CANCER RES, V44, P1216
COMPARATIVE EFFICACY OF CHLOROPHYLLIN IN REDUCING CYTOTOXICITY OF SOME HEAVY-METALS
被引：16
作者：
GHOSH, AK
SEN, S
PALIT, S
GHOSH, A
SHARMA, A
TALUKDER, G
机构：
[1] Genetic Toxicology Unit, Centre of Advanced Study in Cell and Chromosome Research, Department of Botany, Calcutta University, Calcutta, 700019, 35, Ballygunge Circular Road
来源：
BIOLOGY OF METALS
|
1991年
/
4卷
/
03期
关键词：
CHLOROPHYLLIN;
CLASTOGENICITY;
BONE MARROW;
D O I：
10.1007/BF01141307
中图分类号：
Q5 [生物化学];
Q7 [分子生物学];
学科分类号：
071010 ;
081704 ;
摘要：
The potential of chlorophyllin in reducing clastogenicity was studied against two concentrations of each of three potent metallic clastogens (cesium chloride, mercuric chloride and cobalt chloride) in bone marrow cells of mice in vivo. The respective salts and chlorophyllin were administered orally to mice by gavaging in different combinations. Simultaneous administration of chlorophyllin with both concentrations of each salt reduced the clastogenic effects in the order Cs > Hg > Co. Chlorophyllin could not decrease the clastogenic effects when administered 2 h before the salts.
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页码：158 / 161
页数：4
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