USE OF 0.3-PERCENT TRICLOSAN (BACTI STAT-ASTERISK) TO ERADICATE AN OUTBREAK OF METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS IN A NEONATAL NURSERY

被引:106
作者
ZAFAR, AB
BUTLER, RC
REESE, DJ
GAYDOS, LA
MENNONNA, PA
机构
[1] Department of Infection Control, Arlington Hospital Arlington, VA
[2] Department of Pathology, Arlington Hospital Arlington, VA
[3] Department of Pediatrics/Neonatology, Arlington Hospital Arlington, VA
[4] Department of Administration, Arlington Hospital Arlington, VA
[5] Quality Assessment, Arlington Hospital Arlington, VA
关键词
D O I
10.1016/0196-6553(95)90042-X
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background: Once established in an institution, methicillin-resistant Staphylococcus aureus (MRSA) outbreaks have proved difficult to eradicate, despite intensive infection control measures. This report describes the nosocomial infection with MRSA of 22 male infants in a neonatal nursery during a 7-month period and the infection control procedures that effectively brought this outbreak under control and eliminated recurrence for more than 31/2 years. Methods: After a single index case of bullous impetigo caused by MRSA in a neonate discharged from the nursery 2 weeks previously, an additional 18 cases of MRSA skin infections were clustered in a 7-week period. Aggressive infection control measures were instituted, including changes in umbilical cord care, circumcision procedures, diapers, handwashing, gloves, gowns, linens, disinfection, placement in cohorts of neonates and staff, surveillance, and monitoring. Results: These measures were not effective in slowing the outbreak. The single additional measure of changing handwashing and bathing soap to a preparation containing 0.3% triclosan (Bacti-Stat) was associated with the immediate termination of the acute phase of the MRSA outbreak. Conclusion: The nursery has remained free of MRSA for more than 31/2 years, attesting to the success of our program.
引用
收藏
页码:200 / 208
页数:9
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