DELETIONAL TYPES OF ALPHA-THALASSEMIA IN CENTRAL JAVA']JAVA

被引：4

作者：

TAN, JAMA ^{[1
]}

TAY, JSH ^{[1
]}

SOEMANTRI, A ^{[1
]}

KHAM, SKY ^{[1
]}

WONG, HB ^{[1
]}

LAI, PS ^{[1
]}

SAHA, N ^{[1
]}

机构：

[1] UNIV DIPONEGORO,SEMARANG,INDONESIA

来源：

HUMAN HEREDITY | 1992年 / 42卷 / 05期

关键词：

HAPLOTYPES; SUBTYPES; MOLECULAR GENETICS; TRIPLICATE GENE; ALPHA-THALASSEMIA;

D O I：

10.1159/000154084

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The frequency of deletional alpha-thalassaemia in a Javanese population sample (n = 103) was investigated at three restriction sites of the alpha-globin gene (BamHI, BglII and RsaI). The overall gene frequency of alpha+ deletional thalassaemia was found to be very low (0.03). Leftward (-alpha4.2) and rightward (-alpha3.7) deletions and triplicated genes were present in equal frequency (0.015 and 0.005, respectively).

引用

页码：289 / 292

页数：4

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