AN EXAMPLE OF REGIOSELECTIVE ESTERIFICATION BY INTRAMOLECULAR ACYL TRANSFER FROM A TERTIARY AMINE

被引：13

作者：

WADDELL, TG

RAMBALAKOS, T

CHRISTIE, KR

机构：

[1] Department of Chemistry, University of Tennessee at Chattanooga, Chattanooga

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 15期

关键词：

D O I：

10.1021/jo00302a055

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Despite the fact that the famous antimalarial quinine (1) has been known for 170 years, there is still considerable interest in its chemical and biological properties. Much of the most recent attention is due to the utility of quinine as a chiral resolving agent and catalyst.1 In addition, however, malaria is still a worldwide problem, and quinine is the only antimalarial toward which resistance of theparasite Plasmodium falciparum has not yet been reported.2 Important and new chemistry of quinine may yet be discovered. © 1990, American Chemical Society. All rights reserved.

引用

页码：4765 / 4767

页数：3