USE OF CHARGED AND NEUTRAL CYCLODEXTRINS IN CAPILLARY ZONE ELECTROPHORESIS - ENANTIOMERIC RESOLUTION OF SOME 2-HYDROXY ACIDS

被引：135

作者：

NARDI, A

ELISEEV, A

BOCEK, P

FANALI, S

机构：

[1] CNR, IST CROMATOG,AREA RIC ROMA,VIA SALARIA KM 29300, CP 10, I-00016 MONTEROTONDO, ITALY

[2] CZECHOSLOVAK ACAD SCI, INST ANALYT CHEM, CS-61142 BRNO, CZECHOSLOVAKIA

来源：

JOURNAL OF CHROMATOGRAPHY | 1993年 / 638卷 / 02期

关键词：

D O I：

10.1016/0021-9673(93)83435-U

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Enantiomers of racemic 2-hydroxy acids, namely 2-phenyllactic, 3-phenyllactic. mandelic, m-hydroxymandelic, p-hydroxymandelic and 3,4-dihydroxymandelic acid, were resolved by capillary zone electrophoresis. The separation was achieved by using the background electrolyte with addition of cyclodextrins. The effects of the type of cyclodextrin, the pH of the electrolyte and the shape of analyte compounds on the migration time and resolution were studied. Good resolution was obtained with background electrolytes in the pH range 5-7, supplemented with 2-hydroxypropyl, 6A-methylamino- and 6A,6D-dimethylamino-beta-cyclodextrin.

引用

页码：247 / 253

页数：7

共 22 条

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