STEREOSELECTIVE ADDITION OF ORGANOCOPPER REAGENTS TO CYCLIC N-ACYLIMINIUM IONS

被引：33

作者：

LUDWIG, C ^{[1
]}

WISTRAND, LG ^{[1
]}

机构：

[1] LUND UNIV,CTR CHEM,S-22100 LUND,SWEDEN

来源：

ACTA CHEMICA SCANDINAVICA | 1994年 / 48卷 / 04期

关键词：

D O I：

10.3891/acta.chem.scand.48-0367

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Addition of alkylcopper reagents to the chiral N-acyliminium ion 2a occurs with a high degree of trans selectivity, in contrast with the addition of pi-nucleophiles, where cis selectivity has been observed. A mechanism involving the formation of a pre-complex has been proposed in order to account for this selectivity.

引用

页码：367 / 371

页数：5

共 27 条

[21] INTRAMOLECULAR REACTIONS OF N-ACYLIMINIUM INTERMEDIATES [J].