HIV-1 PROTEASE SPECIFICITY OF PEPTIDE CLEAVAGE IS SUFFICIENT FOR PROCESSING OF GAG AND POL POLYPROTEINS

被引：256

作者：

DARKE, PL ^{[1
]}

NUTT, RF ^{[1
]}

BRADY, SF ^{[1
]}

GARSKY, VM ^{[1
]}

CICCARONE, TM ^{[1
]}

LEU, CT ^{[1
]}

LUMMA, PK ^{[1
]}

FREIDINGER, RM ^{[1
]}

VEBER, DF ^{[1
]}

SIGAL, IS ^{[1
]}

机构：

[1] MERCK SHARP & DOHME RES LABS, DEPT MED CHEM, W POINT, PA 19486 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1988年 / 156卷 / 01期

关键词：

D O I：

10.1016/S0006-291X(88)80839-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：297 / 303

页数：7

共 25 条

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[6] GENOME ORGANIZATION AND TRANSACTIVATION OF THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-2
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[7] DIRECT MICROSEQUENCE ANALYSIS OF POLYPEPTIDES USING AN IMPROVED SEQUENATOR, A NON-PROTEIN CARRIER (POLYBRENE), AND HIGH-PRESSURE LIQUID-CHROMATOGRAPHY
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[8] INHIBITION OF RETROVIRAL PROTEASE ACTIVITY BY AN ASPARTYL PROTEINASE-INHIBITOR
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[J]. NATURE, 1987, 329 (6140) : 654 - 656
[9] ACTIVE HUMAN IMMUNODEFICIENCY VIRUS PROTEASE IS REQUIRED FOR VIRAL INFECTIVITY
KOHL, NE
EMINI, EA
SCHLEIF, WA
DAVIS, LJ
HEIMBACH, JC
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (13) : 4686 - 4690
[10] SYNTHETIC PEPTIDES AS SUBSTRATES AND INHIBITORS OF A RETROVIRAL PROTEASE
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (12) : 4185 - 4189

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