cAMP signal transduction pathways regulating development of Dictyostelium discoideum

被引：61

作者：

Kimmel, Alan R. ^{[1
]}

Firtel, Richard A. ^{[2
]}

机构：

[1] NIDDK, Lab Cellular & Dev Biol, NIH, 6-B1-22, Bethesda, MD 20892 USA

[2] Univ Calif San Diego, Ctr Mol Genet, Dept Biol, La Jolla, CA 92093 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1991年 / 1卷 / 03期

关键词：

D O I：

10.1016/S0959-437X(05)80304-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Dictyostelium discoideum development is regulated through receptor/G protein signal transduction using cAMP as a primary extracellular signal. Signaling pathways will be discussed as well as the regulation and function of individual cAMP receptors and G alpha subunits. Finally potential downstream targets including protein kinases and nuclear events will be explored.

引用

页码：383 / 390

页数：8

共 56 条

[51]

SNAARJAGALSKA BE, 1988, DEV GENET, V9, P215

[52]

SON TJ, 1991, GENE DEV, V5, P572

[53] DEVELOPMENTALLY REGULATED PROTEIN-TYROSINE KINASE GENES IN DICTYOSTELIUM-DISCOIDEUM [J].

TAN, JL ;

SPUDICH, JA .

MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (07) :3578-3583

[54]

THEIBERT A, 1986, J BIOL CHEM, V261, P5121

[55] CHEMOATTRACTANT AND GUANOSINE 5'-[GAMMA-THIO]TRIPHOSPHATE INDUCE THE ACCUMULATION OF INOSITOL 1,4,5-TRISPHOSPHATE IN DICTYOSTELIUM CELLS THAT ARE LABELED WITH [H-3]INOSITOL BY ELECTROPORATION [J].

VANHAASTERT, PJM ;

DEVRIES, MJ ;

PENNING, LC ;

ROOVERS, E ;

VANDERKAAY, J ;

ERNEUX, C ;

CAMPAGNE, MMV .

BIOCHEMICAL JOURNAL, 1989, 258 (02) :577-586

[56] DIRECT INDUCTION OF DICTYOSTELIUM PRESTALK GENE-EXPRESSION BY DIF PROVIDES EVIDENCE THAT DIF IS A MORPHOGEN [J].

WILLIAMS, JG ;

CECCARELLI, A ;

MCROBBIE, S ;

MAHBUBANI, H ;

KAY, RR ;

EARLY, A ;

BERKS, M ;

JERMYN, KA .

CELL, 1987, 49 (02) :185-192

← 1 2 3 4 5 6 →