T-CELL RESPONSES IN MALARIA

被引：11

作者：

HVIID, L ^{[1
]}

JAKOBSEN, PH ^{[1
]}

ABUZEID, YA ^{[1
]}

THEANDER, TG ^{[1
]}

机构：

[1] UNIV COPENHAGEN,INST MED MICROBIOL,DK-1168 COPENHAGEN,DENMARK

来源：

APMIS | 1992年 / 100卷 / 02期

关键词：

MALARIA ANTIGENS; T-CELLS; IMMUNE RESPONSE;

D O I：

10.1111/j.1699-0463.1992.tb00846.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Malaria is caused by infection with protozoan parasites of the genus Plasmodium. It remains one of the most severe health problems in tropical regions of the world, and the rapid spread of resistance to drugs and insecticides has stimulated intensive research aimed at the development of a malaria vaccine. Despite this, no efficient operative vaccine is currently available. A large amount of information on T-cell responses to malaria antigens has been accumulated, concerning antigens derived from all stages of the parasite life cycle. The present review summarizes some of that information, and discusses factors affecting the responses of T cells to malaria antigens.

引用

页码：95 / 106

页数：12

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