REGULATORY MECHANISMS THAT COORDINATE SKELETAL-MUSCLE DIFFERENTIATION AND CELL-CYCLE WITHDRAWAL

被引：315

作者：

LASSAR, AB

SKAPEK, SX

NOVITCH, B

机构：

[1] Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115

来源：

CURRENT OPINION IN CELL BIOLOGY | 1994年 / 6卷 / 06期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0955-0674(94)90046-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Skeletal muscle differentiation entails the coupling of muscle-specific gene expression to terminal withdrawal from the cell cycle. Several models have recently been proposed which attempt to explain how regulated expression and function of myogenic transcription factors ensures that proliferation and differentiation of skeletal muscle cells are mutually exclusive processes.

引用

页码：788 / 794

页数：7

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