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THE EFFECTS OF AGING IN RATS ON WORKING AND REFERENCE MEMORY PERFORMANCE IN A SPATIAL HOLEBOARD DISCRIMINATION TASK

被引：76
作者：
VANDERSTAAY, FJ
VANNIES, J
RAAIJMAKERS, W
机构：
[1] STATE UNIV LIMBURG,DEPT NEUROPSYCHOL & PSYCHOBIOL,POB 616,6200 MD MAASTRICHT,NETHERLANDS
[2] UNIV NIJMEGEN,DEPT COMPARAT & PHYSIOL PSYCHOL,6500 HE NIJMEGEN,NETHERLANDS
来源：
BEHAVIORAL AND NEURAL BIOLOGY | 1990年 / 53卷 / 03期
关键词：
D O I：
10.1016/0163-1047(90)90226-V
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
The effects of aging on spatial memory performance of rats was studied in a holeboard task in which 4 of 16 holes were baited with food. Brown-Norway rats of five ages (4, 13, 19, 25, and 30 months) received a total of 80 acquisition trials. A clear age-related decline of spatial working and reference memory performance was found. The decline was most profound between 19 and 25 months of age. The speed of visiting holes and the development of a preferred pattern of hole-visits did not influence spatial discrimination performance. Correlational analysis supported the view that the working and reference memory measures represent distinct aspects of spatial memory. © 1990 Academic Press, Inc.
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页码：356 / 370
页数：15
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