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ON STEROIDS .367. SYNTHESIS OF RIA HAPTENS - 3-ALPHA,11-ALPHA-DIHYDROXY-5-ALPHA-PREGNAN-20-ONE 11-HEMISUCCINATE

被引：5
作者：
KASAL, A
PASZTOROVA, S
机构：
来源：
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 1993年 / 58卷 / 03期
关键词：
D O I：
10.1135/cccc19930619
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
5alpha-Pregnane-3alpha,11alpha-diol-20-one (XVII) was prepared by hydroxylation od 5alpha-pregnan-3alpha-ol-20-one (XVI) by Rhizopus nigricans and by chemical conversion of 11alpha-hydroxyprogesterone (1). The diol XVII was partially acylated with 2-(trimethylsilyl)ethyl hydrogen succinate and the 11alpha-succinate XVIII was converted to the target 11alpha-hemisuccinate XXI.
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页码：619 / 628
页数：10
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