ON STEROIDS .367. SYNTHESIS OF RIA HAPTENS - 3-ALPHA,11-ALPHA-DIHYDROXY-5-ALPHA-PREGNAN-20-ONE 11-HEMISUCCINATE

被引：5

作者：

KASAL, A

PASZTOROVA, S

机构：

来源：

COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 1993年 / 58卷 / 03期

关键词：

D O I：

10.1135/cccc19930619

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

5alpha-Pregnane-3alpha,11alpha-diol-20-one (XVII) was prepared by hydroxylation od 5alpha-pregnan-3alpha-ol-20-one (XVI) by Rhizopus nigricans and by chemical conversion of 11alpha-hydroxyprogesterone (1). The diol XVII was partially acylated with 2-(trimethylsilyl)ethyl hydrogen succinate and the 11alpha-succinate XVIII was converted to the target 11alpha-hemisuccinate XXI.

引用

页码：619 / 628

页数：10

共 16 条

[11] MICROBIOLOGICAL TRANSFORMATIONS OF STEROIDS .1. INTRODUCTION OF OXYGEN AT CARBON-11 OF PROGESTERONE [J].