MANIPULATION OF RADIOBIOLOGICAL HYPOXIA IN A HUMAN-MELANOMA XENOGRAFT TO EXPLOIT THE BIOREDUCTIVE CYTO-TOXICITY OF RSU-1069

被引：10

作者：

COLE, S

STRATFORD, IJ

ADAMS, GE

机构：

来源：

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY | 1989年 / 56卷 / 05期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1080/09553008914551781

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：587 / 591

页数：5

共 12 条

[1] RADIATION SENSITIZATION AND CHEMOPOTENTIATION - RSU-1069, A COMPOUND MORE EFFICIENT THAN MISONIDAZOLE INVITRO AND INVIVO [J].

ADAMS, GE ;

AHMED, I ;

SHELDON, PW ;

STRATFORD, IJ .

BRITISH JOURNAL OF CANCER, 1984, 49 (05) :571-577

[2] THE EFFECT OF HYDRALAZINE ON THE TUMOR-CYTOTOXICITY OF THE HYPOXIC CELL CYTOTOXIN RSU-1069 - EVIDENCE FOR THERAPEUTIC GAIN [J].

CHAPLIN, DJ ;

ACKER, B .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1987, 13 (04) :579-585

[3] THE RADIOSENSITIZING AND TOXIC EFFECTS OF RSU-1069 ON HYPOXIC CELLS IN A MURINE TUMOR [J].

CHAPLIN, DJ ;

DURAND, RE ;

STRATFORD, IJ ;

JENKINS, TC .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1986, 12 (07) :1091-1095

[4]

COLE S, 1989, IN PRESS RADIOTHERAP

[5] EXPERIMENTAL PHARMACOKINETICS OF RSU-1069 AND ITS ANALOGS - HIGH TUMOR PLASMA RATIOS [J].

DEACON, JM ;

HOLLIDAY, SB ;

AHMED, I ;

JENKINS, TC .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1986, 12 (07) :1087-1090

[6] RADIOTHERAPY USING THE HYPOXIC CELL SENSITIZER RO 03-8799 IN MALIGNANT-MELANOMA [J].

DISCHE, S .

RADIOTHERAPY AND ONCOLOGY, 1987, 10 (02) :111-1116

[7] THE DIFFERENTIAL CYTOTOXICITY OF RSU 1069 - CELL-SURVIVAL STUDIES INDICATING INTERACTION WITH DNA AS A POSSIBLE MODE OF ACTION [J].

STRATFORD, IJ ;

WALLING, JM ;

SILVER, ARJ .

BRITISH JOURNAL OF CANCER, 1986, 53 (03) :339-344

[8] RSU-1069, A NITROIMIDAZOLE CONTAINING AN AZIRIDINE GROUP - BIOREDUCTION GREATLY INCREASES CYTOTOXICITY UNDER HYPOXIC CONDITIONS [J].

STRATFORD, IJ ;

ONEILL, P ;

SHELDON, PW ;

SILVER, ARJ ;

WALLING, JM ;

ADAMS, GE .

BIOCHEMICAL PHARMACOLOGY, 1986, 35 (01) :105-109

[9]

STRATFORD IJ, 1987, RADIAT RES, V2, P737

[10]

WALLING JM, 1989, CANCER CHEMOTH PHARM, V24, P28

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