EFFECT OF EXOGENOUS ATP ON VOLUME OF TA3 ASCITES TUMOR CELLS

被引：44

作者：

STEWART, CC

GASIC, G

HEMPLING, HG

机构：

[1] University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania

来源：

JOURNAL OF CELLULAR PHYSIOLOGY | 1969年 / 73卷 / 02期

关键词：

D O I：

10.1002/jcp.1040730206

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

When exogenous ATP is added to suspensions of TA3 ascites tumor cells suspended in Ca++ and Mg++ free media, a significant increase in cell volume can be measured. This increase is reversible upon addition of Ca++ and/or Mg++ back to the media. The enlargement of these cells is temperature sensitive and specific for ATP; no other nucleotides, EDTA or ouabain were effective. The evidence suggest that this phenomena may be due to an alteration in membrane permeability and that the regulation of membrane permeability is an energy dependent process. Copyright © 1969 Wiley‐Liss, Inc.

引用

页码：125 / &

共 34 条

[21]

NACHMAN RL, 1967, J CLIN INVEST, V46, P138

[22] FURTHER STUDIES ON MYOFIBRILLAR ADENOSINE TRIPHOSPHATASE-INHIBITORY ACTIVITY AND MB++-DEPENDENT ADENOSINE TRIPHOSPHATASE OF RELAXING GRANULES [J].