THE EFFECTS OF CLOZAPINE ON TARDIVE-DYSKINESIA

被引：267

作者：

LIEBERMAN, JA

SALTZ, BL

JOHNS, CA

POLLACK, S

BORENSTEIN, M

KANE, J

机构：

[1] ALBERT EINSTEIN COLL MED,PSYCHIAT,NEW YORK,NY

[2] YESHIVA UNIV ALBERT EINSTEIN COLL MED,PSYCHIAT,BRONX,NY 10461

[3] HILLSIDE HOSP,INPATIENT UNIT,NEW YORK,NY

[4] ST JOHNS UNIV,STAT,JAMAICA,NY 11439

[5] HILLSIDE HOSP,DEPT PSYCHIAT,NEW YORK,NY

来源：

BRITISH JOURNAL OF PSYCHIATRY | 1991年 / 158卷

关键词：

D O I：

10.1192/bjp.158.4.503

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

This article reviews eight published studies that describe clozapine's effects on TD and examines the outcome of 30 patients with TD treated with clozapine for up to 36 months. These data indicate that TD response to clozapine is variable but that approximately 43% of cases, particularly those with dystonic features, improved after clozapine treatment. Methodological limitations of the studies described, however, preclude definitive conclusions, which must await appropriately controlled trials.

引用

页码：503 / 510

页数：8

共 35 条

[1] EVIDENCE FOR DIFFERENT STATES OF THE DOPAMINE D1 RECEPTOR - CLOZAPINE AND FLUPERLAPINE MAY PREFERENTIALLY LABEL AN ADENYLATE CYCLASE-COUPLED STATE OF THE D1-RECEPTOR [J].