MOLECULAR MICROANALYSIS OF PATHOLOGICAL SPECIMENS IN SITU WITH A LASER-RAMAN MICROPROBE

被引:56
作者
ABRAHAM, JL [1 ]
ETZ, ES [1 ]
机构
[1] NBS,CTR ANALYT CHEM,NATL MEASUREMENT LAB,WASHINGTON,DC 20234
关键词
D O I
10.1126/science.493979
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A laser-Raman microprobe has been used to identify microscopic inclusions of silicone polymer in standard paraffin sections of lymph node. This example of organic chemical microanalysis in situ in pathological tissue represents an extension of microanalytical capabilities from elemental analysis, performed with electron and ion microprobes, to compound-specific molecular microanalysis. Copyright © 1979 AAAS.
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页码:716 / 718
页数:3
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